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Video from the incident showed smoke rising from beneath the rocket before it erupted into a large fireball. The explosion marks another setback for the company, which is owned by Jeff Bezos.
Officials respond as investigation follows recent setbacks
Florida congressman Mike Haridopolos said he was in contact with NASA Administrator Jared Isaacman following the blast, adding that he was relieved there were no injuries and praised first responders and engineers.
The incident comes after another setback last month, when New Glenn failed to place a communications satellite into the correct orbit, prompting an investigation into the mission.