Deadly rain-related floods and landslides are common across South Asia during the monsoon season from June to September, but experts say climate change is increasing their frequency and severity.
Entire neighbourhoods in Kathmandu were inundated over the weekend with flash floods reported in rivers coursing through the capital and extensive damage to highways connecting the city with the rest of Nepal.
Nepal's home ministry said 104 people had been killed across the country with another 64 still missing.
Ministry spokesman Rishi Ram Tiwari said that bulldozers were being used to clear several highways that had been blocked by debris, cutting Kathmandu off from the rest of the country.
"More than 3,000 people have been rescued," he added.
At least 14 of those killed were aboard two buses and were buried alive when earth from a landslide careened into a highway south of Kathmandu, Dhading district chief Rajendra Dev Pandey stated.
The valley in which the capital sits recorded 240 millimetres (9.4 inches) of rain in the 24 hours to Saturday morning, the country's weather bureau told the Kathmandu Post newspaper.
It was the highest rainfall recorded in the capital since at least 1970, the report said.