Residents of Burqa said Israeli settlers entered their village, threw rocks and set fire to cars.
"The youth of the village went out to confront them using stones. Settlers opened fire, they killed one person and wounded others," said one witness who asked not to be named.
The Palestinian health Ministry said a 19-year-old died in the incident. The Israeli military said it was looking into the report.
Earlier on Friday, near the West Bank city of Tulkarm, the Israeli military said soldiers shot at suspects who fired weapons and hurled explosives and stones at its troops. It said hits were identified and reported no injuries to its forces.
The Palestinian Health Ministry said an 18-year-old was shot in the head and killed. Amjad Zeidan, who said he witnessed the incident from about 200 metres away said that he did not see the youth killed carrying weapons or explosives.
The Palestinian Foreign Ministry condemned the killing as a "field execution" and called on the International Criminal Court to "break its silence and promptly complete its investigation into the crimes of the occupation".