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Real Madrid suffered a major setback in its title defense campaign after the defeat to Real Betis. The loss puts their chances of securing the title at risk.
Isco, the former Real Madrid player, scored the winning goal for Real Betis from a penalty kick in the 54th minute. This came after Moroccan Ibrahim Dias gave Real Madrid the lead in the 10th minute. American Johnny Cardoso equalized for Betis in the 34th minute.
Real Madrid's points total remains at 54, keeping them in second place. The loss puts them in a direct confrontation with Barcelona, the current league leader. Barcelona will face Real Sociedad on Sunday and has a golden opportunity to widen the gap by three points.