Chelsea's first Premier League points of the season and the first for new manager Enzo Maresca arrived in spectacular fashion as the visitors ripped Wolves apart after the break following an absorbing first period.
Maresca's side led twice in the first half with goals by Nicolas Jackson and Palmer but both times Wolves deservedly hit back through Matheus Cunha and Jorgen Strand Larsen.
Wolves fell part after the break, however, and Madueke took the game beyond them with three goals in 15 minutes.