Authorities said late Saturday they had re-gained control of the prison in Guayaquil for a second time in as many days after President Guillermo Lasso's spokesman said fighting had again broken out earlier in the day.
In the initial riot that began Friday night prisoners fought with "savagery," said Pablo Arosemena, governor of the province of Guayas where the prison is located.
The riot began around 7:00 pm Friday when prisoners tried to enter Block 2 of the jail where their rivals were held, firing gunshots, detonating explosives and swinging machetes, and prompting police to move in.
At least 68 prisoners were killed and another 25 were wounded, according a statement which the Ecuador Prosecutor's Office posted on Twitter.
In the second outbreak of fighting Saturday, inmates from two other blocks attacked each other, said presidential spokesman Carlos Jijon.
He confirmed a little while later that police had pushed through to the prison's interior and that the situation was "under control."