The two new routes were introduced a day after Etihad's new summer service to Mykonos, making it three new destinations launched in just over 24 hours.
The inaugural Malaga service, EY148, took off at 10:28 and landed at 15:48 local time. The service is scheduled for Wednesdays and Fridays between 9th July and 15th September on a Dreamliner B787.
The inaugural Santorini flight, EY177, took off from Abu Dhabi at 11:10 and landed at 14:18 local time. The service is scheduled to be operated on Fridays and Sundays between 9th July and 12th September on an Airbus A320.